Barrett's esophagus is an acquired metaplastic abnormality in which the normal stratified squamous epithelium lining of the esophagus is replaced by an intestinal-like columnar epithelium.

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(Inflammatory Bowel Diseases) Esopredict, a novel validated methylation-based biomarker assay, could help distinguish high-risk Barrett's esophagus from low-risk disease. (American Journal of ...

Barrett's esophagus usually develops in the context of chronic gastroesophageal reflux. Presumably, the repeated exposure to acid and bile in the refluxate induces tissue injury in the lower ...