Wegener's granulomatosis, microscopic polyangiitis (MPA), Churg–Strauss syndrome, and primary pauci-immune crescentic glomerulonephritis are associated with circulating anti-neutrophil cytoplasmic ...

mPA can affect the gastrointestinal tract in 30% of cases and result in abdominal pain, diarrhea, and bleeding. Peripheral neuropathy occurs in about a third of patients. Myalgias and arthralgias are ...

DESTIN, Fla. — Practical, individualized care for patients with antineutrophil cytoplasmic antibody-associated vasculitis should use the presence of granulomatosis with polyangiitis, rather than ...

Standard therapy for vasculitis associated with antineutrophil cytoplasmic antibodies can achieve high rates of remission, but with the risk of serious toxic effects. The results of a ...

-- Primary endpoint achieved: CCX168 demonstrates numerical superiority and achieves statistical significance in test for non-inferiority in BVAS response relative to standard of care -- -- Treatment ...

MOUNTAIN VIEW, Calif., Dec. 3, 2013 (GLOBE NEWSWIRE) -- ChemoCentryx, Inc., (Nasdaq:CCXI), today announced positive top-line data from the first two steps of a Phase II trial with CCX168, an inhibitor ...

Despite the frequency of coronary artery calcification among patients with antineutrophil cytoplasmic antibody-associated vasculitis, only 25% were using statins. A significant percentage of patients ...

ST. GALLEN, Switzerland & MOUNTAIN VIEW, Calif.--(BUSINESS WIRE)--Regulatory News: Vifor Fresenius Medical Care Renal Pharma (VFMCRP) and ChemoCentryx, Inc., (NASDAQ:CCXI) today announced positive ...

ChemoCentryx CCXI announced that it has received approval in the European Union (EU) for its drug, Tavneos (avacopan), to treat adult patients with anti-neutrophil cytoplasmic autoantibody-associated ...

A 79-year-old keen cyclist from Willunga man credits positive thinking with saving him from a rare disease, ANCA vasculitis, after he experienced severe pains while in Thailand. Roger Fabray, 79, was ...

In March 1998, the patient was a 19-year-old girl with a 10-day history of emesis, myalgia, arthralgia, and weight loss, who was found on routine physical examination to have edema in her face and ...