The regulation of intracellular calcium is pivotal in driving various cellular processes, including proliferation, apoptosis, migration and gene transcription. In cancer, aberrant calcium signalling ...

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ...

Cells have to invest a lot of energy to maintain this concentration gradient, especially when it comes to getting rid of calcium. 'It's like being on a rush-hour train in a city like Tokyo. When the ...

A new method exposes key details of the mechanism behind calcium signaling in prokaryotes for the first time. Working in a Listeria monocytogenes model, researchers from Umeå University (Sweden) led ...

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ...

Uncovering the mechanisms behind plant defense signaling can improve strategies to protect crops against disease.

The 8-Bromo-cAMP sodium salt PKA activator, a synthetic analog of cAMP, is one of the most potent tools of investigating and playing with this pathway, which has become an essential part of ...

Plants are increasingly encountering abiotic stressors, such as salinity, drought, heavy metals, microplastics, and various environmental contaminants, that ...

The nonapeptide Oxytocin is a cyclic nine-amino‐acid peptide that has long been studied for its possible roles in ...

A new study published in the journal Science Signaling has found that an immune system protein plays a central role in the ...