Cell–cell junctions form the structural and functional backbone of multicellular tissues, coupling adhesive complexes with the actomyosin cytoskeleton to regulate barrier function, tissue remodelling ...

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation ...

Endothelial cell junctions form a dynamic interface that governs vascular permeability, tissue perfusion and homeostasis. The principal adhesive structures—adherens junctions and tight junctions—are ...

Our body consists of ~30 trillion cells. These cells need to tightly attach to each other to maintain the integrity of our body. However, we are constantly exposed to mechanical stress, which ...

A billion-year-old calcium signaling system in cyanobacteria reveals surprisingly ancient roots of cell-to-cell communication ...

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

Our bodies and organs are shielded from the external environment by tissue barriers like the skin. These barriers must be tightly sealed to prevent unwanted substances from entering. This sealing is ...