During embryonic development, somatic cells maintain monoallelic expression of imprinted genes, but germ cells need to be imprinted to reflect the sex of the embryo. For example, if a paternally ...
And these are showing that speciation can be produced not only because of incompatible genetic interactions, but also because of epigenetic control of gene expression, like imprinting.” ...
ICRs regulate the expression of imprinted genes – genes where only one parental copy of the gene is active, while the other copy is silenced early in development. Imprinted genes are of special ...
Presently, the exact role of methylation in gene expression is unknown ... of birth defects that appear to be caused by defective imprinting mechanisms (Robertson, 2005). The results of these ...
For example, DNA methylation modifies gene expression without altering the nucleotide sequence. A well-studied DNA methylation-based phenomenon is genomic imprinting (ie, genotype-independent ...
According to the imprinted brain theory, paternal gene expression may cause a child to have a larger brain, develop more quickly, and demand more from the mother. Maternal gene expression may ...
This is not the case in genomic imprinting, which gets reset in each generation. The results from the Burga group cement the evolutionary link between parent-specific gene expression and host ...