The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly ...

Figure 1: Schematic diagram to illustrate the principal elements of extracellular calcium homeostasis. These receptors comprise a subfamily (family C) of the G-protein-coupled-receptor superfamily.

The kidneys play a vital role in determining health and lifespan. Their primary function is to eliminate waste products and surplus fluids from the body via urine. This intricate process of excretion ...

The kidneys play a dominant role in regulating both the volume and composition of the extracellular fluid. They function to ensure that the body maintains a homeostatic internal environment. They ...

BOSTON - While investigating the underlying causes of a rare skin disorder, a researcher at Massachusetts General Hospital (MGH) discovered a previously unknown mechanism in the kidneys that is ...