The Los Angeles Rams and the San Francisco 49ers take the field in one of many compelling matchups on the NFL schedule in Week 10. In terms of live coverage, we have what you need to know about Week 10 of the NFL here. Check out the piece below.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Sunday Late Afternoon Kickoff s Arizona Cardinals at Seattle Seahawks, 3:05 p.m., CBS Los Angeles Rams at San Francisco 49ers, 3:25 p.m., FOX Detroit Lions at Washington Commanders, 3:25 p.m., FOX

With several players set to debut for new teams, we're sorting Week 10's Sunday games by post-trade deadline intrigue.

NFL Week 10 announcers, channels, streaming information, times for all 14 games on the NFL Week 10 schedule this week. Who is announcing each game?

Several potential NFL playoff teams are in crucial matchups in Week 10 of the season. The league will also host a game in Berlin, Germany.

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's 2025 NFL Week 10 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine. New users can get $50 in Pick6 credits at DraftKings when they play $5.