Researchers at the John Innes Centre in the United Kingdom, working with Kobe University in Japan, have engineered a plant ...

Slices of living human brain, taken during neurosurgery and kept alive in the lab, released far less of the inflammatory messenger interleukin-1 beta once a drug blocked a receptor called P2X7.

For patients with nonarteritic anterior ischemic optic neuropathy (NAION), glucagon-like peptide-1 (GLP-1) receptor agonist ...

A research team at Leipzig University has identified a mechanism in adhesion G protein-coupled receptors (adhesion GPCRs), a specific group of membrane receptors. This mechanism is essential for the ...

Neurokinin receptor (NKR) antagonists are already widely used for treating menopausal hot flashes, representing a highly ...

Researchers show that the ligand-independent nuclear receptor BmERR uses its AF-2 domain to recruit the coactivator PPRC1 and ...

Five modulators, one receptor, very different risk profiles. Andrea De Censi, MD, calls low-dose tamoxifen a new standard for prevention; others want more evidence.

A review published in Genes & Diseases highlights the prostaglandin E2 receptor subtype 4 (EP4) as an important regulator of ...

A new study describes an exciting discovery that changes the way we understand human bitter taste receptors. The research has revealed a hidden "pocket" inside one of the body's bitter taste receptors ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...

Grünenthal announced today that the first patient has been enrolled in KF7040-21, a Phase II trial to investigate the efficacy, safety and tolerability of its proprietary nociceptin receptor (NOP) ...