It would have to continue sans Riker and Troi (Jonathan Frakes and Marina ... This fits into "Star Trek" chronology, as "Nemesis" took place in 2379 and "Prodigy" takes place in about 2384.

After a joyous wedding between William Riker and Deanna Troi, Captain Picard and the Enterprise crew stumble upon a positronic signature which results in a prototype version of the android Data.