ADARs are enzymes that bind to double-stranded RNA (dsRNA) molecules and make a specific base edit, converting a mismatched adenosine (A) molecule into inosine (I). This change destabilizes the dsRNA ...
Gene therapy has been heralded as the new frontier of medicine, but there are still many limitations to current technologies; among them, how to deliver therapeutic genes to specific cells, and only ...
More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far ...