Ashley Zambelli opens up to PEOPLE about discovering that she tested positive for trisomy 21 — also known as Down syndrome — after her three kids also tested positive for the mutation.

Children's chapter books have gotten better at representing kids with disabilities, but I struggled to find ones where the main character had Down syndrome. "Our stories tell us who matters enough ...

Children with Down syndrome show characteristic physical features which consist of a flat facial appearance together with upward-facing eyes, a palm crease, and low muscle tone.

Rodriguez’s views prompted a backlash on social media among families who have children with Down syndrome. One viewer, Maria, made a TikTok video with an image of her young son with Down ...

Most other Down syndrome programs nationwide focus on children, even though many people with the condition now live into middle age and often develop health problems typically associated with seniors.

Two-year-old Stella Tremonti —with parents Mark and Victoria— waves to gathered guests during the opening of the SMILE with Stella Tremonti Down Syndrome Clinic at the AdventHealth for ...

To mark World Down Syndrome Day on March 21, Fox News contributor Tom Shillue headed to Times Square to speak with a father of a girl with Down syndrome about common misperceptions.