Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme—P4HA1 prolyl hydroxylase, ...

Researchers have described the neurodegeneration that occurs in the nervous system of the bowel in Batten disease, a rare and fatal genetic condition. In their latest study, a team showed that gene ...

Researchers at Washington University School of Medicine in St. Louis have described the neurodegeneration that occurs in the ...

Trethera Corporation (“Trethera”), a clinical stage biopharmaceutical company committed to developing novel drugs targeting ...

There’s no cure for the skin condition, but a new study shows that self-guided talk therapy can help a person deal with the itching. Online self-guided cognitive behavioral therapy (CBT) that teaches ...

The drug target of AIs is the enzyme aromatase ... This is the therapeutic principle used in the antihormonal AI treatment of ER-positive postmenopausal breast cancer.

intended for the treatment of IBD, as well six other inflammatory conditions across rheumatology and dermatology. “We are in a time where biosimilars for Crohn’s disease and ulcerative colitis ...

"Our findings not only add two additional enzymes with novel modes of activity to this group of proteins but also suggest how targeted treatment could be identified for diseases in which ...

The nanoGLA therapy, based on the use of peptide-targeted nanoliposomes, effectively delivers the deficient enzyme GLA, encapsulated in the nanoliposomes, to the organs most affected by this disease.