The New England Patriots will take on the Los Angeles Chargers on Saturday afternoon at Gillette Stadium for their second-to-last game of the season. Ahead of the matchup, they downgraded center Ben Brown to out due to a concussion.

The Los Angeles Chargers will be without one of their running backs for Saturday's game against the New England Patriots. Running back Gus Edwards will not play due to an ankle injury. He's been out of practice these last two days.

The LA Chargers (9-6) take on the New England Patriots (3-12), kicking off a tripleheader of Saturday games in Week 17. Kickoff from Gillette Stadium is at 1 p.m. ET (NFL Network). Let's analyze

The New England Patriots are winless in their last five games (six weeks including the bye), and on Saturday, they'll host the Los Angeles Chargers at Gillette Stadium in Foxboro, Massachusetts. New England's 3-12 record has already eliminated them from the postseason, but a win would be beneficial for their confidence to end a frustrating season.

SportsLine's model simulated Saturday's Los Angeles Chargers vs. New England Patriots matchup 10,000 times and revealed its NFL best bets