Studies of Parkinson's disease have long overlooked Pacific populations—meta-analysis shows why that must change
A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows ...
TFE3 Unlocks New Avenues For Parkinson's Disease Treatment
TFE3 overexpression attenuates α-Syn toxicity in a mouse model of Parkinson's disease. TFE3 overexpression rescues autophagy defects of dop ...
Medscape1mon
Therapy for Dyskinesias in Parkinson's Disease Patients
Understanding the pathogenesis of LID has contributed ... of dyskinesia as a motor complication in the course of Parkinson's disease (PD) includes a spectrum of involuntary movements schematically ...
Scientists Just Found a Cholesterol Clue That Could Change Parkinson’s Treatment
A breakthrough study has uncovered a hidden player in Parkinson’s disease—24-OHC, a cholesterol metabolite that fuels the ...
The New York Times26d
Drug Similar to Ozempic Failed to Treat Parkinson’s Disease in a Trial
A rigorous study that randomly assigned Parkinson’s patients to take exenatide, a relative of Ozempic, showed absolutely no benefit or slowing of the course of the degenerative disease after 96 ...
China Internet Information Center7d
Parkinson's possible to be blocked thanks to Chinese scientists' breakthrough research
The battle against Parkinson's disease, the second most common ... As a result, further in-depth research into the disease's pathophysiology and targeted treatments is crucial, according to ...
eLife13d
Parkinson’s disease-associated Pink1 loss disrupts vesicle trafficking in Ensheathing glia causing dopaminergic neuron synapse loss
The preliminary data presented in this manuscript seem valuable. The data are currently incomplete and there are numerous technical concerns, some of which may arise from insufficient description of ...
Science Daily12d
Uncovering novel transcriptional enhancers in neuronal development and neuropsychiatric disorders
Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory roles in non-coding regions remain largely unclear. Using the LUHMES neuronal ...