The San Francisco 49ers activated running back Christian McCaffrey from the Injured Reserve list and safety Tashaun Gipson Sr. from the team's practice squad.

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to ...

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to discuss his journey to the pros, the early contributions of the rookie class and ...