Secretary of State Marco Rubio defended President Donald Trump's interest in acquiring Greenland and gaining control over the Panama Canal, deeming it crucial for U.S. national security interests.

President Donald Trump continues to advance his agenda with executive actions ahead of a deadline to impose tariffs on imports from Canada and Mexico this weekend. Follow for live updates.

Rubio has to balance aggressive Trump policies with Latin America's willingness to cooperate. The Panama Canal will be contentious.

Secretary of State Marco Rubio's first stop this weekend will be Panama City as Trump' administration shifts back Washington's focus to Latin America.