For over a decade, scientists have been growing organoids - small clusters of cells that mimic a particular organ - to serve ...

For over a decade, scientists have been growing organoids—small clusters of cells that mimic a particular organ—to serve as ...

Stanford scientists have solved a key conundrum in keeping organoids — lab-grown clusters of cells that resemble human organs — alive. These mini-brains and mini-hearts mimic human organs and enable ...

Precursors to left Purkinje fibers, left bundle branch ... both in mouse embryos and potentially in embryonic stem cells or other pluripotent stem cells. Cardiac arrhythmias, often consequent to ...

Researchers identified compounds that expand the number of the healthy stem cells in the lungs, heart, joints, and eyes. (The concept of using small molecules this way is based on an earlier ...

Cardiovascular disease and kidney disease are two of the most urgent issues in global public health. In the United States ...

Cardiac perfusion was performed with 0.1 M phosphate-buffered ... then imaged with a Zeiss AxioCam MRc 5 camera mounted on a Zeiss Axio Zoom.V16 microscope. Brains from Purkinje cell-specific ...

Wholemount immunohistochemistry of the cerebellum reveals striped Purkinje cell loss across the cerebellar cortex of some aged mice. A) Wholemount cerebellum of a 16-month-old mouse immunostained for ...

In this study, researchers characterized the development of Purkinje cells — large neurons located in the cerebellar cortex, crucial for motor control and coordination — and interneurons. Purkinje ...

In the past decades, numerous preclinical studies and several clinical trials have evidenced the feasibility of cell transplantation in treating heart diseases. Over the years, different delivery ...

Starting with over 3,600 neurons from over 180 Neuropixels recordings from two labs, they distilled it into a library of just over 200 spikes consisting mostly of Purkinje cell simple and complex ...