The San Francisco 49ers certainly have had some bad luck so far this season and are dealing with some high-profile injuries.

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

San Francisco 49ers left tackle Trent Williams found a possible silver lining in all the injuries the team is dealing with ...

The San Francisco 49ers started off Week 3 on the right foot. After absences and limited participations littered their first ...

Purdy still hasn't entirely shaken the "system" quarterback label and other denigrations. A chance for his rebuttal is now ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 ...