Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Facilities operated by the US Department of Energy (DOE) are required to have extensive worker safety and health programs by regulation. We describe how Argonne National Laboratory (ANL) has ...

The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein localization and function in living cells. These hybrid probes are constructed by diverse site-specific ...

Plasmonic nanostructures with hollow interiors have emerged as a class of multifunctional materials for many applications owing to their superior plasmonic activities relative to their solid ...

File Submission Submit your own Manuscript PDF File—and provide your native LaTeX manuscript package as a ZIP archive. Compress the following into a single ZIP archive (.zip) file: Main body of the ...

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Food-derived peptides, as dietary supplements, have significant effects on promoting brain health and relieving central nervous system (CNS) diseases. However, the blood–brain barrier (BBB) greatly ...

In this study, the mechanism and microkinetics of 1-butene catalytic cracking were investigated. Based on the calculation results of the full reaction, the optimal paths for 1-butene isomerization and ...

Metathesis and reversible catalytic reactions are fundamentally intriguing and powerful tools in modern synthetic chemistry. While most reversible catalytic reactions are predicated on breaking and ...