Background: Observational studies have suggested that sodium-glucose cotransporter 2 inhibitors (SGLT2i) are associated with a lower risk of atrial fibrillation (AF) recurrence after catheter ablation ...

Background: Chronic insomnia affects up to one-third of adults, and over-the-counter melatonin is increasingly promoted as a “cardiometabolic-friendly” sleep aid. Robust data on its long-term ...

The 2025 AHA/ACC High Blood Pressure Guideline reflects the latest recommendations and advancements in hypertension research and clinical practice. This curated collection of commentaries and ...

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Deoxycorticosterone acetate-salt hypertension (DOCASH) and sham rats were prepared following previously established methods 1; vasoconstriction and western blot experiments followed standard protocols ...

Hypertension affects over 1.3 billion people, and it is a major contributor to death and morbidity from cardiovascular disease and stroke. iRAS (inhibitors of the renin-angiotensin system) are used ...

During this century, the roles of aldosterone and its receptor—the mineralocorticoid receptor (MR)—in diseases has expanded greatly. Twenty-five years ago, they were assumed to be involved in a minor ...