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  1. Desmin - Wikipedia

    Desmin is a protein that in humans is encoded by the DES gene. [5][6] Desmin is a muscle-specific, type III intermediate filament [7] that integrates the sarcolemma, Z disk, and nuclear membrane in …

  2. Pathology Outlines - Desmin

    Desmin stain is a 52kDa cytoplasmic intermediate filament present in muscle and endothelial cells; expressed in neoplasms with myogenic differentiation

  3. What Is Desmin: Function, Gene, and Disease - ScienceInsights

    4 days ago · Desmin is a protein that holds muscle cells together. Learn how it works, what happens when its gene mutates, and how doctors diagnose and treat desmin-related diseases.

  4. Desmin: Definition – MyPathologyReport

    Desmin is a protein found inside cells that form muscle tissue. It helps provide structure and support within muscle cells, allowing them to contract and function properly. Desmin is part of a group of …

  5. Desmin variants: Trigger for cardiac arrhythmias? - PMC

    Desmin (DES) is a classical type III intermediate filament protein encoded by the DES gene. Desmin is abundantly expressed in cardiac, skeletal, and smooth muscle cells.

  6. Desmin - an overview | ScienceDirect Topics

    Desmin is defined as the major muscle-specific intermediate filament protein that is highly expressed in heart tissue and plays a crucial role in cardiac development, accounting for 2% of cellular protein in …

  7. DES gene: MedlinePlus Genetics

    The DES gene provides instructions for making a protein called desmin. Desmin is found in heart (cardiac) muscle and in the muscles used for movement (skeletal muscle). Within muscle fibers, …

  8. Desmin: a major intermediate filament protein essential for the ...

    Nov 15, 2004 · Desmin is a muscle-specific protein and a key subunit of the intermediate filament in cardiac, skeletal and smooth muscles.

  9. Desmin variants: Trigger for cardiac arrhythmias? - Frontiers

    Sep 9, 2022 · Desmin (DES) is a classical type III intermediate filament protein encoded by the DES gene. Desmin is abundantly expressed in cardiac, skeletal, and smooth muscle cells.

  10. Molecular insights into the role of desmin intermediate filament ...

    Oct 16, 2025 · Here, we investigated the role of desmin in cardiac differentiation and homeostasis across embryogenesis, postnatal life, and adulthood, as well as under various stimuli.